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Timing of clinical outcomes in CKD with severely decreased GFR

Age (30-85 yrs)
Race (White or Black)
eGFR (mL/min/1.73m²)
Systolic Blood Pressure (mmHg)
History of Cardiovascular Disease
Urine Albumin to Creatinine (mg/g)
Click to change between mg/g and mg/mmol
Smoking History

 Any Kidney Replacement Therapy (KRT a.k.a. ESRD)      19.7%  
 Any Cardiovascular Disease (CVD) 11.3% 
 Any Death 15.4% 

CKD G4+ - no event    63.1%
KRT Only   13.8%
KRT After CVD    0.4%
CVD After KRT    1.3%
Death After KRT    3.4%
Death After KRT and CVD    0.8%
Death After CVD    2.8%
Death Only   8.4%
CVD Only   6.0%

                     CKD G4: Chronic Kidney Disease Stage G4 (eGFR <30 mL/min/1.73m²)      CVD: Cardiovascular Disease     KRT: Kidney Failure Requiring Kidney Replacement Therapy     GFR: Glomerular Filtration Rate

          The events are mutually exclusive. So, "Death After CVD"  means "Death After CVD, without the occurrence of KRT",  etc. "Death After CVD and KRT"  includes "Death After CVD After KRT"  and "Death After KRT After CVD"

Grams ME, Sang Y, Ballew SH, Carrero JJ, Djurdjev O, Heerspink HJL et al. Predicting timing of clinical outcomes in patients with chronic kidney disease and severely
                                                                                    decreased glomerular filtration rate. Kidney Int 2018; 93:1442-1451

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